Toxic

Toxic

The Problem with High Fructose Corn Syrup

By Ben Fuchs | Pharmacist Ben

The next time you see that commercial where the two people are trying to figure why high fructose corn syrup is problematic, here’s somethings YOU can think about…

Table sugar is made up robust chemical bond that connects fructose and glucose; it’s a natural product with a natural bonding that makes it very strong. High fructose corn syrup, which is made up of an artificially processed combination of fructose and glucose has no such chemical constituency. The two sugars aren’t bonded. And that means it’s is fructose is free and easily absorbed by liver which doesn’t really know how to handle kind of fructose load. High Fructose Corn SyrupThe net result is a too horrible words that when it comes to your health and longevity that you don’t want to hear together “fatty liver”.

High fructose sweeteners have another unpleasant quality. While all sugars can make you fat, fructose-fat may be specific for the belly. In a study published in the Journal of Clinical Investigation, researchers showed that volunteers who consumed fructose sweetened beverages experienced significantly higher accumulations of fat within the abdomen even though they and their glucose drinking experimental colleagues gained the same amount of total weight.

Got gout? Well, it turns out one of the ways the the liver handles all that excess fructose ends up creating the uric acid crystals that wreak so much havoc in millions of big toes around the country. And uric acid doesn’t just cause the grief of gout. It associated with high blood pressure and kidney disease too.

And if that’s not enough, there’s recent literature that suggests that even though fructose doesn’t raise insulin, it may increase insulin resistance. In article published earlier this year in Diabetes Care, fructose consumers were more likely to have depotentized insulin than glucose consumers.

Perhaps the worst thing about high fructose corn syrup is a particularly distressing feature it shares in common with most common sweeteners, artificial and “natural”. They make you want to eat more. In the book ‘Salt Sugar Fat” by Michael Moss, there’s an interesting and revealing vignette about how surprised researchers were to discover that sweetened beverages more hungry not less. And now it turns out that fructose may be particularly culpable. Two papers in the Proceedings of the National Academy of Sciences in 2007 showed that pure glucose decreases food intake while fructose had the opposite effect fructose increased it .

Posted by Ben Fuchs in Toxic

Big Pharma: The PolyPill Has No Clothes

By Ben Fuchs | Pharmacist Ben

The PolyPill Has No Clothes. Polypharmacy is defined as the use of multiple medications to treat an individual patient. Given the toxicity of even a single pharmaceutical, it is an especially inelegant medical technique and soon it won’t even have to involve taking lots of pills practice. That’s because scientists are working feverishly to produce the world’s first “polypill”, a four-in-one combination pill, which is supposed to cut the predicted risk of stroke and heart disease in half.

PolyPillNo mention is made however, in the glowing drug company promotional material for the high-tech medication monster 4-plex, of whether side effects are also quadrupled. Composed of four off-patent drugs, aspirin, a cholesterol lowering statin and two blood pressure drugs (and ACE inhibitor and a diuretic) , the polypill, in my opinion, simply represents another egregious attempt by drug companies to extract hard-earned dollars from patients and insurance companies by painting old-time inelegant medical interventions with a shiny new coat of marketing and product positioning.

In any case, the best protection from stroke and heart disease remains lowering blood sugar and insulin levels, nutritional supplementation with cardiac friendly nutrients like the B-vitamins, Vitamin C and essential fatty acids and moderate exercise.

Posted by Ben Fuchs in Toxic

Warfarin Toxicity

By Ben Fuchs | Pharmacist Ben

Of all the deadly health destroying poisonous drugs in the pharmacy, it would be difficult to come up with one that has more toxicity than warfarin. Traditionally used as rat poison, warfarin (brand name Coumadin), which claims 4 million patient/victims in the United States, (over 1 percent of the American public!) is used by physicians to keep the blood in a fluid state.

Blood clotting is serious business and according to the National Blood Clot Alliance as many as 2 million of them occur every year, with up to 300,000 of them fatal. Thus the rational for the use of powerful blood thinning gents like warfarin would seem to be sound. After all, what’s wrong with a little rat poison if it keeps the blood in a fluid state and reduces the risk of a potentially life-threatening clot? The problem is, the clotting mechanisms of the blood are intricate and sophisticated. Coagulation is a tightly regulated biochemical function and to override these mechanisms requires some serious chemical poison. Warfarin ToxicityThrowing a pharmaceutical monkey wrench into this highly controlled system is a dangerous proposition and indeed the line between desired blood thinning effects and adverse reactions, toxicities and even death is razor thin.

Not to worry though, for now our friends in the world of pharmaceuticals have come to the rescue. Yesterday the FDA announced their latest drug approval for “Kcentra” a new pharmaceutical marketed by CSL Behring, specifically mandated to stop severe bleeding associated with the use of warfarin. Great, now we have another drug to take care of the side effects of an original drug. Although no mention in the FDA press release is made of the side effects of Kcentra, you can bet they will occur and they will be significant. According to CSL Behring, some potential problems associated with the use of their new drug include stroke, pulmonary embolism, and deep vein thrombosis, in addition to more mundane side effects like headache, nausea/vomiting, joint pain and low blood pressure.

Blood delivers oxygen and nutrients and its facile movement through the body is an absolute requirement for good health. If the body has initiated blood clotting chemistry inappropriately something is seriously amiss. Thus clotting usually involves a response to some kind of emergency condition such as a surgery, wounding, lack of nutrition, hypoxia (low oxygen) or the entrance of toxicity (e.g. from food, cigarette smoke or drugs) into the sacred sanctum of the blood.

That means the best way to keep blood in its optimum fluid state is to make sure you’re doing everything you can do to stay healthy. First of all it’s imperative, as always, that a priority is placed on digestive wellness. Nothing will cause the blood to clot faster than the entrance of food particles through a leaky gut. Make sure you’re staying away from problem foods, using probiotics, glutamine powder and apple cider vinegar. Digestive enzymes can provide a one-two anti-clotting punch. When taken with food they can improve digestion and reduce the likelihood of undigested food particles getting into the blood. And when taken on an empty stomach they can actually help dissolve clots and thin the blood. Vitamin E and Omega-3 fatty acids have blood thinning properties, and timed-release niacin, while not directly thinning the blood, can have a blood vessel opening effect that may improve circulation. And perhaps the most important strategy for maintaining blood fluidity involves oxygen. A couple of minutes of deep breathing is always a good idea, even if you don’t have blood clotting problems. And, if your blood is tending to get sticky it can be a life-saver. If you have a smart phone, you may want to invest in a deep breathing app like “Breathing Zone” or “My Calm Beat”. Even something as simple as a daily two or three minute bounce on a mini-trampoline can be a helpful drug and doctor free strategy for keeping blood circulating and flowing efficiently.

Posted by Ben Fuchs in Toxic

Fungicidal Effects of Zoloft

By Ben Fuchs | Pharmacist Ben

If you’re on the prescription drug Zoloft, it’s a good thing you’re not a fungus! Scientists experimenting with the effects of the best-selling anti depressant have discovered that the well—known pharmaceutical has a major toxic effect on yeast cells. It distorts their normally curved membranes and triggers the cell to start eating themselves. According to pharmacologist Ethan Pearlstein of Princeton University, yeast doesn’t have any serotonin, so there’s no reason to expect any effect, let alone such a bizarre suicidal one. According to Pearlstein, a molecule of Zoloft “…should be completely innocuous to a yeast cell, the way an antibiotic would be innocuous to a viral infection”.

ZoloftWhat exactly the clinical implication are, of this self destructive response to Zoloft, for patients taking the drug, remains to be seen, but the unexpected findings has pharmacologists salivating at the prospect of new targets for the next generation of anti-depressants. In the words of author Pearlstein: “Altogether, our work suggests that the serotonin-based theory might be an oversimplification and that the cause of depression is not a closed story.” The question of whether or not this toxic effect on yeast can make Zoloft an effective anti-fungal agent has not yet been addressed, but it may be something that pharmaceutical companies will be looking into for future research.

In a paper published in the journal Clinical Infectious Diseases, doctors describe the fungicidal effects of Zoloft on three patients being treated for depression with concomitant vaginal yeast infections. Apparently all three patients experienced improvements in symptoms associated with their fungal infections while taking the anti-depressant medication. The researchers concluded: “The potential offered by sertraline (Zoloft) against fungi is sufficiently great to merit further studies by investigators in the field of infectious diseases…To support potential systemic use, animal models and clinical trials are highly warranted.”

Posted by Ben Fuchs in Toxic

Top 12 Tips and Tools for Easy Detoxification Part 2

By Ben Fuchs | Pharmacist Ben

While genetic tendencies (and epi-genetic factors) as well as stress and poor nutrition play an important role in illness, underlying almost all manifestations of poor health is toxicity. And I’m talking about both internal and external toxicity which are obviously related. Human beings have been saturating their outer and inner environments with poison since the dawn of history. These days, we actually enter the world as a toxic mess. Even newborn babies have been shown to have high levels of toxic pollutants. In 2005 Greenpeace published a report titled “Hazardous Chemicals in Umbilical Cord Blood” where they concluded that hazardous chemicals are a common occurrence in umbilical cord blood. Newborns tested out at a whopping average of 287 toxins, 180 of which were known carcinogens!

Easy DetoxificationToxic air can be filled with literally hundreds of deadly and carcinogenic compounds, (some like chemtrails intentionally deposited there for no “known” reason), not to mention radioactive waste from disasters like Chernobyl and Fukushima. When human fat biopsies are performed styrene, dioxins, xylene and dichlorobenzene among other unsavory, unhealthy and potentially carcinogenic chemicals shows up in 100% of cases. There are deadly chemicals in water too, fluoride and chlorine may arguably provide benefits, but no one can discount their truly toxic nature. Water is also a source of other unpleasant drinking material including prescription drugs and industrial (and even human) waste. Pesticides are an especially serious problem. Measurable levels have been found in breast fluid from mother’s milk around the world, including Eskimos living in the North Pole, thousands of miles from source of the nearest farm or fruit orchard. Internally there is no way to know exactly how much toxicity we’re dealing with, but it’s safe to say the average person’s detox system is probably being overloaded. Food, stress, trauma, experiences in addition to interfacing (really integrating) with our toxic external environment can put quite a load on the body’s ability to clean itself out and over time lots of nasty stuff can end up in various bodily fluids and tissues.

But it’s important to recognize that indeed we have a detox system. In fact the human body is remarkably well equipped to handle a lot of poison! But it needs certain substances to do its work. In a later post we’ll talk about the liver and what’s known as Phase 1 and Phase 2 detoxification, but for now let’s just say there are some key nutrients we should all be using to keep the poisons our bodies have to deal with the more manageable level. Maybe we’ve done such a number on our planet that there’s no way we can completely clean it up but let’s not forget that the human being grew up in a world filled with natural poisons too. There are chemical processes built into the body to allow it to detoxify and purify itself, but by and large these processes require raw materials in the form of nutrients. Last post we listed Part One of the top 12 Detox supplements, focusing on treatment and non-nutritional approaches. Below is Part two of the Top 12 detoxification nutritional supplements (with apologies to fans of the B-complex, alpha-lipoic acid, probiotics and fiber, which while important for detox, did not make this list) for supporting the body’s ability to detoxify in an unfortunately very toxic world.

1. MSM 500-1000mg daily, NAC 100-500mg daily. both contains sulfur which is a key player in biological detoxification. Sulfur attracts (chelates) heavy metals and is an important component of the glutathione system, perhaps the most powerful detox system in all of biochemistry. Provide protection from lead and mercury poisoning. Sulfur even has anti-inflammatory properties. It’s probably a good idea to use MSM (absorbable sulfur) and the sulfur amino acid cysteine in the form of NAC (so potent a detoxifier that it’s part of the emergency room protocol for liver poisoning) on a daily basis.

2.Selenium 200-400mcg daily – important for activation of the glutathione, the major human biological detoxification molecule. Protects fats from oxidation and is specific for protection from heavy metals like mercury. Selenium is the most important trace mineral for anti-oxidant defense. Powerful anti-cancer protectant, important for cardiovascular and thyroid health too. This is one you can take too much of so keep your daily dose under 800mcg daily. For optimum effects take as selenomethionine. Garlic, onions and cruciferous vegetables are great food sources of this important mineral.

3.Vitamin E 400 iu daily – Important for keeping fats in cell membranes and organs from oxidation and heavy metal assault. Important fro recycling anti-oxidant detox substances like Vitamin C and glutathione. Works synergistically with selenium. Tocotrienol form more protective than tocopherol form.. Especially protective for smokers (lung) and alcoholics (liver). Improves detoxification of pharmaceuticals. May also decrese the effectiveness of medications (which is of course a consequence of their toxicity). This one is difficult to get from foods so supplementation is a must.

4.Glutamine 1-5 grams daily- essential for the production of glutathione, the body’s major detoxification substance. Required for liver detoxification pathways and works synergistically with Vitamin C, E and selenium. Importance for digestive health also support detox functions. Most abundant amino acid in the body, relevant for health of all cells.

5.Vitamin C 1 to 10 grams daily – Spectacularly important nutrient for detoxification and immune system support. Works synergistically with Vitamin E, selenium and glutathione. Protects against cancer and heavy metal poisoning. Provides neutralizing protection from lead. May provide protection from chlorine. Sucrose (sugar) reduces its effectiveness. Especially effective against radiation. Improves elimination of toxins through bowel movements. Non-toxic in even very high doses.

6.Good Minerals– nutritional minerals protect against heavy metal poisoning by minerals with similar electromagnetic properties. Zinc protects against cadmium (smokers are especially at risk from cadmium in tobacco). Calcium, magnesium and zinc provide protection from aluminum. Iron, copper and zinc help may keep lead toxicity at bay. Iodine provides protection from bromine and fluorine and radioactive iodine (e.g. Fukushima). BTW, if you’re interested in testing your nutritional status, ask for an RBC (red blood cell) test. The most accurate measurements for nutrient levels and heavy metal toxicity are done directly on cells NOT plasma, the watery/protein portion of blood.

Posted by Ben Fuchs in Toxic