Vitamin E

Asthma Epidemic

By Ben Fuchs | Pharmacist Ben

Get ready for another epidemic! According an article posted on cnn.com the annual “September Asthma Epidemic” (their words, not mine) is coming, although the only evidence they cite are clinical studies that have shown the greatest number of hospitalization due to asthmatic attack are highest 17 days after labor day. Whether an epidemic is on the way or not may be up to conjecture, but what is not debatable is the well-documented fact that asthma is a big and getting bigger problem. From 2001 to 2010, the asthma incidence increased almost 15 percent. By 2009, asthma accounted for nearly 3,400 deaths, nearly 480,000 hospitalizations, 1.9 million emergency department visits, and 8.9 million physician office visits.

Asthma Epidemic

By BruceBlaus (Own work), via Wikimedia Commons

Asthma, which affects almost 13 percent of adults, and over 29 million Americans at least once in their lives is best thought as an inflammatory condition of the airways. The airways are the passageways where air, or more specifically oxygen, gets transferred into the blood. The net effect is an obstruction or a blockade of oxygen which causes the wheezing and shortness of breath, and a sense of suffocation that occurs with a asthmatic attack. The key word in the above description is inflammatory, which alludes to the microscopic blockages where inhaled oxygen from the air we breathe is transferred to the blood.

And inflammation? Well, that’s always the manifestation of a jacked-up immune system. ALWAYS! I can think of no more fundamental concept in all of physical health. Inflammation is the way a defensive (immune) response shows up; a defensive response to some kind of stressor. And a defensive/stress response means something is getting into the body or something is happening to the body that the body perceives as an attack. In order for a DEFENES-ive response to be initiated there has to be a preceding OFFENSE-ive agent; And the main routes for an offensive agent to get into the body for a defensive response to be triggered, such as those observed with an ordinary asthmatic attack, are typically through the lungs (they are breathed in) or the digestive system (they are eaten). In the case of exercise induced asthma the stress results from the need to heat and humidify large amounts of air that enter into the lungs during exercise.

So what’s an asthmatic to do? Though the medical treatments of choice are inhalers, which are usually some kind of steroid type drug or a nervous system agent that dumbs down respiratory responsiveness or suppresses immunity. Pharmacological intervention is not without toxicity or side effects. The questions for asthmatics are: Do you really want to suppress the immune system that is so essential for protecting the body from the environment assaults, animate and inanimate Or, do you really want to dial down your nervous system that distributes the electrical energy that runs our bodies and brains?

In my opinion the best way to deal with asthma is to take a healthy, natural and multi-pronged approach. In the case of asthmatic attacks that are directly caused by something you’re eating, obviously you want to eliminate those kinds of foods. Dairy and grains are likely suspects. Sometimes legumes, including peanuts and soy, can be problematic. Even vegetables can induce an asthmatic attack in those who are predisposed. Be especially careful of the nightshades which include tomatoes, potatoes, eggplants and peppers.

In addition to avoiding foods that can trigger asthmatic attacks it’s important to reduce the load on the immune system, from non-triggering substances that simply burden the immune system without directly causing respiratory symptoms. If there are predisposing immune loads(mostly problem foods), these can contribute to the signs of inhalation asthma albeit without directly causing asthmatic symptomology. Even if it doesn’t seem like there is a connection between foods and asthmatic symptoms, foods can still PREDISPOSE even if they don’t immediately CAUSE an asthmatic attack. This is kind of tricky, because the connection between predisposing factors that weaken the immune system or burden the immune AND immediate triggers might not be obvious. You might think your asthmatic symptoms are the result of exposure to pollen, not realizing that the pollen is merely the trigger and the cause is really an overburdened immune system that is struggling to keep up with food allergens or toxins that are getting into the body on a regular basis, even if they are not causing immediate symptoms or problems. I call it the “straw-that-breaks-the-camel’s-back” effect where the inhaled substance is not the actual cause but merely the “straw-that-breaks-the-camel’s-back”. What’s worse, if you have an immune system that is burning through nutrients or if you are malnourished, either because you’re not absorbing or nor getting nutrients this undernutriation can also be a contributing factor.

Look for other indicators of immune activation. Skin problems, rashes, frequent colds, autoimmune disease are all signs. If you have any of these symptoms associate with them foods and eliminate those foods. And if you don’t have any of those symptoms, then look for digestive difficulties. And really look. Bowel movement issues and gas are especially good clues. So is heart burn. If you have any of these symptoms connect them to food and eliminate those foods. This will decrease the burden on the immune system and reduce the “straw-that-breaks-the camel’s-back-effect”.

And don’t forget to add in the digestive support nutrients including probiotics, digestive enzymes with food, glutamine powder, juices of aloe vera and noni. There are also important nutrients for the lungs and blood and immune system. Magnesium is an asthmatic’s best nutritional friend. It can help relax constricted blood vessels and strengthen the immune system too; use 1000-2000mg of the glycinate form. Vitamin C is especially important for lung health. I’d be using 100-5000 mg a day. Vitamin E is also an important respiratory nutrient. Use the tocotrienol form, 400 IU daily, for best results. Vitamin E’s cousin, CoQ10 can be helpful, use the oil soluble gel-caps and take 100mg a day. And don’t forget about Vitamin D which can provide respiratory health benefits and beef up a burdened immune system. Sun exposure is always the best way to get your Vitamin D, but if you prefer to go the supplement route, take 5,000 to 10,000 IU. And always balance out your Vitamin D supplementation with Vitamin A, which can provide its own respiratory health benefits. I’d be taking 20,000 IU of Vitamin A at least 4 or 5 days a week. It’s stored in liver so missing a day or two isn’t going to hurt. Don’t forget your EFAs especially Omega-3 s from fish oil which can have wonderfully beneficial benefits for addressing the inflammation associated with asthma. Finally, in addition to supporting digestive health, probiotics can strengthen the immune system and keep it from being so sensitive and jumpy. Take 80 billion units a day and look for products that contain multiple strains of good bacteria.

Posted by Ben Fuchs in Health

Adult Persistent Acne or APA

By Ben Fuchs | Pharmacist Ben

SUMMARY

  • Millions of Americans have Adult Persistent Acne
  • APA? Think adrenal and ovary/testes hormones
  • Causes as always: digestive, insulin, blood sugar, adrenal stress
  • Ovarian involvement sometimes results in cysts in the ovaries.  This condition is called Poly Cystic Ovarian Syndrome
  • Symptoms include obesity, blood pressure issues fertility development of body hair, loss of head hair and oily skin and blemishes
  • For all APA use nutrition, diet and lifestyle strategies, they work!

 

Think zits are for kids?  Think again!  According to The International Dermal Institute between 40 and 55 percent of the adult population age 20-40 have with low grade, persistent acne and oily skin.That means millions of unfortunate Americans and what’s even more disconcerting is the fact that dermatologists who refer to this condition as Adult Persistent Acne (APA) are, for the most part, impotent and clueless when it comes to addressing this difficult and unpleasant skin condition.  The accepted medical protocols for dealing with APA remain mired in the tired antiquated, decades-old saws of steroids and antibiotics or worse barbaric deep chemical peels using toxic substances and potential carcinogens  like croton oil, phenol or aminolevulenic acid.

Adult Persistent Acne APAWhen it comes to the biology of APA, no health condition screams adrenal and reproductive gland dysfunction louder. Both the adrenals as well as the ovaries/testes produce substances that regulate the skin oil production, pigmentation and skin cell growth that are the hallmark features of adult acne.

To put it simply and concisely, the symptoms of adult persistent acne are a classic case of hormone pathology.  And, hormone pathology is itself more often than not a reflection of digestive and blood sugar problems.

Food toxins and allergies can result in malabsorbtion of raw materials for hormone production In fact, one of the more poorly recognized causes of APA is food intolerance and digestive issues.  If you find that in addition to problem skin you have digestive health issues, including loose stools and/ or constipation, chronic heartburn bloating, gas, or simply general gastrointestinal discomfort and unpleasantness AND you’re breaking out, the chances are pretty good that you’re dealing with some kind of digestive related skin condition.  And once the digestive distress becomes long-term and chronic you’re very possible that you’ll end up dealing with adrenal stress which can then function as a secondary cause of problem skin.  This is especially likely if your facial blemishes appear as rashy and diffuse (spread out all over the face) and if they are showing up on the back or chest or other non-facial parts of the body.

Then there’s blood sugar connection to adult acne.  Elevations in insulin, the sugar controlling hormone are often involved in the development APA.   Once the blood sugar system become overwhelmed, the adrenal activity is unregulated. Many of the more common features of adult persistent acne, especially skin oiliness and hyper-pigmentation are a common sign of adrenal hormone activation.

Even more significant, the dermal distress of APA is more than merely an unsavory superficial skin condition.  The hormone pathology behind the appearance of blemishes, dark spots and oily patches can be the harbinger of much more serious health issues to come.  Because the gland chemicals that are involved in causing adult acne are largely cleared by the lymphatic system, it’s like likely the over the long haul APA can result in congestion in this significant circulatory conduit for biochemical waste.  Because the lymphatic system is charged with eliminating the acne-inducing toxic and old hormones over time congestion of lymph fluid is likely to occur.  Clogging of the lymphatic system may then manifest as immune activity and inflammation and causing even more adult acne, hyper-pigmentation and oiliness.  Ultimately lymphatic congestion can wreak even worse biochemical havoc; liver disease, heart disease and cancer are just some of the ways lymphatic congestion can show up.

As mentioned previously, the hormone issues associated APA may be related to blood sugar dysfunction.  And because of the close connection between blood sugar and female reproductive hormones, women are especially prone to blood sugar induced APA.  Over the course of years and decades of sugar abuse (the average American consumes nearly half a pound a day, far more than the human body is supposed to handling) chronic elevations in insulin are likely.  Insulin as growth inducing substance stimulates cell growth and division.  In the ovaries this rapid cell growth and division can cause cysts.  Ovarian cysts produce symptom hormones and this can be especially problematic for some women.   In fact, elevations ovarian hormones the resulting symptoms, collectively known as Poly Cystic Ovarian Syndrome (PCOS) include weight gain, hair loss and the oily skin and blemishes associated with adult persistent acne.

If you are one of the many unfortunate sufferers of APA don’t despair.  Because ultimately acne like all skin and health conditions is a biochemical/nutrient problem, there are many biochemical/nutrient strategies(as opposed to pharmaceutical) for dealing with APA. Below are my Top 17nutrients and strategies for addressing adult persistent acne:

1)    Zinc Picolinate ( 50mg a day) – best taken with 2mg of Copper chelate, important for blood sugar control as well as hormone production and balance

2)    Vitamin A (20,000 iu a day) – premier skin vitamin stabilized the growth of skin cells and sebum (skin oil) producing cells too

3)    Vitamin B5 (1000-200mg three times a day taking each dose with the entire B-complex) – key vitamin for skin oils and adrenal gland hormones

4)    Vitamin B3 (timed release 100-300 mg daily,taking each dose take with the entire B-complex) – anti-inflammatory, improves blood sugar control

5)    NAC (500-1000mg) a day – important liver support nutrient, improve hormone processing

6)    Selenium Monomethionine (600mcg a day) – detoxification of old hormone

7)    Glutamine (1000 mg a day) – general detoxification and anti-inflammatory properties

8)    MSM (2000mg a day) – detoxification, improve hormone elimination

9)    Vitamin C (5000-10,000 mg a day) – the “primal panacea”, good for everything.  Involved in hormone production as well as blood sugar chemistry

10)   Probiotics (80 billion units of multiple strains) – improves fat metabolism, detoxification and hormone processing

11)    Vitamin E (400 iu a day) – dramatic anti-inflammatory and healing properties

12)   Isolate and eliminate problem foods (dairy, grains eggs and legumes are BIG problem foods; ANY vegetable can be a trigger as well)

13)   Eat lots of cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, bok choy) – improves hormone processing and detoxification.  Steam lightly if you have any thyroid issues

14)   Reduce intake of insulin spiking foods

15)   Reduce intake of ALL foods caloric intake, fasting can have a dramatic impact

16)   Slow down and deepen breathing, deep diaphragmatic breathing techniques daily to improve adrenal function

17)   Exfoliate and cleanse daily 2% salicylic acid toners and cleanser.  Keeping excess skin oils off of the face is important.  These secretions from oil glands, technically called sebum undergo chemical when they’re exposed to air that can cause inflammation and increase zittiness.  Proper and regular exfoliation will assure that potential poor clogging dead skin cells are removed off of the skin surface.

18)   Use Retinoic Acid cream or gel!!  It is by far and away the most important topical skin product you can use.   It improves all markers of skin health including hyper-pigmentation, oily skin and blemish formation.  It’ll even prevent the formation of fine lines and wrinkles.

 

 

Posted by Ben Fuchs in Health

Vitamin E Is Misunderstood

By Ben Fuchs | Pharmacist Ben

Of the six essential vitamins (D, E, A, K, C and the B complex) perhaps none is more misunderstood and unappreciated than Vitamin E. Originally discovered as an anti-sterility factor (tocopherol is Greek for “to bear children”), today Vitamin E is known to provide support for a wide variety of biological systems.

Unfortunately, beneficial levels of this critical fat-soluble nutrient are almost impossible to get from food. The best bets for Vitamin E-containing foods are sunflower seeds, wheat germ oil and rice bran oil. The RDA for Vitamin E is around 22 IU, and according to an article published in The American Journal of Clinical Nutrition, over 93% of Americans don’t even get this minimum amount. This may be one of the main reasons that health issues associated with Vitamin E deficiency are rampant.

Vitamin E Is MisunderstoodFor example, according to Dr. Jeffrey Blumberg of Tufts University , numerous studies indicate that Vitamin E can slow down the production of atherosclerotic plaques, a major cause of heart disease which is a major cause of death in this country. And earlier this week, scientists at Ohio State University published research in the journal Stroke that showed that this important nutrient can protect against stroke, a medical emergency which results in oxygen starvation of brain tissue and affects 800,000 people a year.

And there’s more. According to Dr. Patrick Manning, writing in the journal Diabetes Care, “Vitamin E could have a role to play in delaying the onset of diabetes in at-risk individuals”. Diabetes and pre-diabetes currently affect almost 100 million Americans and the numbers are climbing.

Last year, researchers published an article in the New England Journal of Medicine that showed that Vitamin E can provide relief for many of the estimated 10 million patients who suffer from non-alcoholic fatty liver disease. The author of the study, Dr. Arun J. Sanyal, Chairman of the division of gastroenterology, hepatology, and nutrition at Virginia Commonwealth University said “This clearly shows that vitamin E is effective for treatment of patients with nonalcoholic steatohepatitis (fatty infiltration of the liver). Other studies indicate that vitamin E can help lower blood cholesterol, improve post workout muscle soreness and help provide relief from inflammatory diseases like arthritis and colitis and help reduce risks of developing cancer.

Vitamin E is available in two different classes, tocopherols and tocotrienols, which are then further divided into four subclasses: alpha, beta, delta and gamma, yielding 8 different forms of the essential nutrient. While most supplements only contain alpha tocopherol, each of the eight subclasses has slightly different biological activities. Thus for maximum benefit it may be wise to supplement with both tocopherols and tocotrienols. Look for the word “mixed” on the label as in mixed tocopherols or mixed tocotrienols. This will assure your ingestion of the full range of tocopherols and tocotrienols for the broadest spectrum of Vitamin E activity. A good daily dose is 400 i.u., although like all fatty vitamins, tocopherols and tocotrienols are stored, so missing a day or two shouldn’t be a problem.

 

Posted by Ben Fuchs in Health

Peanuts & Peanut Butter

By Ben Fuchs | Pharmacist Ben

The PeanutThere is no food that speaks to the American childhood experience more clearly than the peanut, the source of that quintessential piece of culinary Americana, peanut butter. Peanuts were originally cultivated in South America by Peruvian Indians who are considered to be the first indigenous groups to domesticate the legume and archaeologists have traced the original specimens to around 5000 BC. From South America the Spanish brought the humble bean to Europe and to their colonies and outposts in what is today the south eastern part of the United States.

Peanuts really caught on during the civil war because they considered to be good, cheap protein. Farmers in the South had pretty much depleted their land of vital nutrients over farming cotton the lowly peanut had come to the rescue as an alternative crop. During and after the civil they ended up in the Northern states where they were sold, freshly roasted by street vendors in NYC and Boston and Philadelphia and a new American love affair was born.

Farming peanuts was a limited and labor intensive affair until the industrial revolution began to change agriculture around the turn of the 20th century. Right around that time George Washington Carver was developing all kinds of stuff from the peanut. All told, Carver, who was the head of the agricultural department at Tuskegee Institute, developed 300 different products with the peanut including various types of soaps and cleansers and milk and even ink! The reason Carver could make so many things out of the peanut is because there are so many incredible chemical active compounds in the plain old peanut.

Their complex nature is also is why peanuts can be such a problem food. In addition to the potentially thyroid suppressing compounds in peanuts, along with grains, dairy, and eggs are one of the most important of all food allergens. While peanut allergies are not as pervasive as as significant as dairy or grain the affect up to 6 million Americans and they be potentially life threatening. I remember when I was a pharmacy student working at an asthma hospital, a kid got an injection that was made with peanut oil and had an allergic reaction that was so severe it killed him. Peanuts can also be source of a toxic mold called aflatoxin that’s been associated with cancer. And unfortunately, peanuts are also a source of really problematic compounds called lectins that trigger various immune and autoimmune reactions.

One of the more common yet underappreciated reactions to peanuts involves the skin. For some sensitive folks, dermatitis can occur by simply by touching or breathing in peanut dust. And ingestion of peanuts has been linked to acne in susceptible children and teenagers.

If you’re looking for concentrated nutrients however, and you’re not concerned with allergic reactions, you’d be wise to add a handful or two of peanuts to a meal a couple of times a week. You can also throw some into a smoothie to enhance its nutritional value. Peanuts are a good source of protein and vitamins, including hard to find vitamin E (one ounce of peanuts contains 29% of the Reference Daily Intake level) as well as minerals like copper, phosphorous, magnesium, iron, potassium, selenium, zinc and calcium. All told, a couple of tablespoonfuls of peanuts contains nearly half of the 13 vitamins necessary for the body’s growth and maintenance and more than one third of the 20 minerals needed! Peanuts are even a good source of resveratrol; one ounce contains approximately 73 mg. A naturally occurring plant compound resveratrol intake is associated with a reduced risk of heart disease and increased longevity.

Posted by Ben Fuchs in Nutrition

Warfarin Toxicity

By Ben Fuchs | Pharmacist Ben

Of all the deadly health destroying poisonous drugs in the pharmacy, it would be difficult to come up with one that has more toxicity than warfarin. Traditionally used as rat poison, warfarin (brand name Coumadin), which claims 4 million patient/victims in the United States, (over 1 percent of the American public!) is used by physicians to keep the blood in a fluid state.

Blood clotting is serious business and according to the National Blood Clot Alliance as many as 2 million of them occur every year, with up to 300,000 of them fatal. Thus the rational for the use of powerful blood thinning gents like warfarin would seem to be sound. After all, what’s wrong with a little rat poison if it keeps the blood in a fluid state and reduces the risk of a potentially life-threatening clot? The problem is, the clotting mechanisms of the blood are intricate and sophisticated. Coagulation is a tightly regulated biochemical function and to override these mechanisms requires some serious chemical poison. Warfarin ToxicityThrowing a pharmaceutical monkey wrench into this highly controlled system is a dangerous proposition and indeed the line between desired blood thinning effects and adverse reactions, toxicities and even death is razor thin.

Not to worry though, for now our friends in the world of pharmaceuticals have come to the rescue. Yesterday the FDA announced their latest drug approval for “Kcentra” a new pharmaceutical marketed by CSL Behring, specifically mandated to stop severe bleeding associated with the use of warfarin. Great, now we have another drug to take care of the side effects of an original drug. Although no mention in the FDA press release is made of the side effects of Kcentra, you can bet they will occur and they will be significant. According to CSL Behring, some potential problems associated with the use of their new drug include stroke, pulmonary embolism, and deep vein thrombosis, in addition to more mundane side effects like headache, nausea/vomiting, joint pain and low blood pressure.

Blood delivers oxygen and nutrients and its facile movement through the body is an absolute requirement for good health. If the body has initiated blood clotting chemistry inappropriately something is seriously amiss. Thus clotting usually involves a response to some kind of emergency condition such as a surgery, wounding, lack of nutrition, hypoxia (low oxygen) or the entrance of toxicity (e.g. from food, cigarette smoke or drugs) into the sacred sanctum of the blood.

That means the best way to keep blood in its optimum fluid state is to make sure you’re doing everything you can do to stay healthy. First of all it’s imperative, as always, that a priority is placed on digestive wellness. Nothing will cause the blood to clot faster than the entrance of food particles through a leaky gut. Make sure you’re staying away from problem foods, using probiotics, glutamine powder and apple cider vinegar. Digestive enzymes can provide a one-two anti-clotting punch. When taken with food they can improve digestion and reduce the likelihood of undigested food particles getting into the blood. And when taken on an empty stomach they can actually help dissolve clots and thin the blood. Vitamin E and Omega-3 fatty acids have blood thinning properties, and timed-release niacin, while not directly thinning the blood, can have a blood vessel opening effect that may improve circulation. And perhaps the most important strategy for maintaining blood fluidity involves oxygen. A couple of minutes of deep breathing is always a good idea, even if you don’t have blood clotting problems. And, if your blood is tending to get sticky it can be a life-saver. If you have a smart phone, you may want to invest in a deep breathing app like “Breathing Zone” or “My Calm Beat”. Even something as simple as a daily two or three minute bounce on a mini-trampoline can be a helpful drug and doctor free strategy for keeping blood circulating and flowing efficiently.

Posted by Ben Fuchs in Toxic